Aragtida Isku-dhafka 2-Bromo-1-[4- (Methylsulfonyl) Phenyl]-1-Ethanone

Jiangsu Jingye Pharmaceuticalwaxay ku faantaa inay soo bandhigto xisaab faahfaahsan oo ku saabsan habka wax soo saarka ee mid ka mid ah xeryahooda calanka, 2-Bromo-1-[4- (Methylsulfonyl) Phenyl] -1-Ethanone, dhexdhexaad ah oo dhexdhexaad ah oo ku saabsan isku-darka daawada.

Hordhac:

2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone, oo caan ku ah u adeegsigeeda isku-dhafka kaarboonyl-ka, waa dhexdhexaad muhiim u ah soo saarista dawooyinka kala duwan, API-yada, iyo kiimikooyinka isku-dhafka caadada ah. Iyada oo leh CAS No. ee 50413-24-6 iyo miisaanka kelli ee 277.14, xaruntan waxaa lagu soo koobay hannaan taxaddar leh oo hubiya tayada sare iyo nadiifnimada.

Habka Isku-dhafka:

Isku-dhafka2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanoneku lug leh dhowr tillaabo oo muhiim ah:

1. Firfircoonida giraanta Phenyl: Nidaamku wuxuu ka bilaabmaa firfircoonida giraanta phenyl si loogu oggolaado falcelinta dambe.

2. Sulfonylation: Soo bandhigida kooxda methylsulfonyl waxay ku dhacdaa falcelinta sulfonylation, iyadoo la adeegsanayo dimethyl sulfate sida wakiilka sulfonylating.

3. Bromination: booska alfa ee acetophenone ayaa markaa la hoos geeyaa bromination, adoo isticmaalaya bromine sida wakiilka halogenating.

4. Nadiifinta: Badeecada cayriin waxa ay martaa nidaam nadiifin adag, oo ay ku jiraan recrystallization iyo chromatography, si loo gaadho heerka la rabo ee daahirsanaanta.

Xaqiijinta Tayada:

Alaabtayadu waxay u taagan tahay suuqa iyadoo ay ugu wacan tahay tayada sare ee ay leedahay, oo ay taageerayaan tallaabooyinka xakamaynta tayada adag. Dufcad kasta waa la tijaabiyaa si loo hubiyo inay buuxisay heerarkayaga sare ee nadiifnimada iyo joogteynta.

Codsiyada:

Xaruntani waxay ka heleysaa isticmaalka ballaaran ee warshadaha dawooyinka, iyada oo u adeegta dhexdhexaadinta isku dhafka maaddooyinka dawooyinka firfircoon ee kala duwan (APIs). Kala duwanaanshaheeda ayaa sidoo kale ka dhigaysa mid ku habboon isku-dhafka caadada iyo cilmi-baarista kiimikada.

Gabagabo:

At Jiangsu Jingye Pharmaceutical, waxaa naga go'an in aan macaamiisheena siino dhexdhexaadyo kiimiko oo tayo sare leh sida 2-Bromo-1-[4-(Methylsulfonyl) Phenyl] -1-Ethanone. U heelanaantayada heerka sare waxay ka muuqataa qiimahayada tartanka, gaarsiinta degdega ah, iyo jawaabta degdega ah ee su'aalaha macaamiisha. Macluumaad dheeri ah ama si aad u dalbato, fadlannala soo xidhiidh:email:guml@depeichem.com/shiyf@depeichem.com. Waxaan rabnaa inaan kaa caawino baahiyahaaga kiimikaad iyo dawooyinka.